The
deadly Ebola epidemic in Liberia could likely be eliminated by June if the
current high rate of hospitalization and vigilance can be maintained, according
to a new model developed by scientists.
Business Standard reports the model, developed by researchers at the University of Georgia (UGA) and
Pennsylvania State University, includes such factors as the location of
infection and treatment, the development of hospital capacity and the adoption
of safe burial practices and is probably the first to include all those
elements.
The
model projected that, if an 85 per cent hospitalization rate can be achieved,
the Ebola epidemic in Liberia should be largely contained by June 2015.
"That's
a realistic possibility but not a foregone conclusion. What's needed is to
maintain the current level of vigilance and keep pressing forward as hard as we
can," said John Drake, an associate professor in the UGA Odum School of
Ecology who led the study published in the journal PLOS Biology.
In
the study, researchers used a mathematical formulation known as branching
processes - a method for keeping track of all possible epidemic outcomes in
proportion to their probabilities - calibrated with newly developed methods.
Drake
and his colleagues started with information gleaned from earlier Ebola
outbreaks.
They included data about variables such as the numbers of patients hospitalized health care workers infected, which allowed them to estimate the level of under-reporting; rates of transmission in hospitals, the community and from funerals; and the effectiveness of infection control measures.
Once they had a working model with plausible parameters, they fine-tuned it using data from the World Health Organization and the Liberia Ministry of Health for the period from July 4 through September 2, 2014.
They included data about variables such as the numbers of patients hospitalized health care workers infected, which allowed them to estimate the level of under-reporting; rates of transmission in hospitals, the community and from funerals; and the effectiveness of infection control measures.
Once they had a working model with plausible parameters, they fine-tuned it using data from the World Health Organization and the Liberia Ministry of Health for the period from July 4 through September 2, 2014.
This
included information about new cases as well as changes in behaviour and public
health interventions during that time, such as the addition of roughly 300
hospital beds and the adoption of safer burial practices.
Liberia
continued to add hospital beds after September 2, so in mid-December, Drake and
his team updated the model to include information collected through December 1.
Using reported data rather than estimates from the earlier version of the model significantly cut down on the range of future possibilities, showing that the response by the Liberian government and international groups had greatly reduced the likelihood of a massive epidemic.
Ebola virus has killed more than 7,800 people, almost all in West Africa, since it broke out a year ago.
Using reported data rather than estimates from the earlier version of the model significantly cut down on the range of future possibilities, showing that the response by the Liberian government and international groups had greatly reduced the likelihood of a massive epidemic.
Ebola virus has killed more than 7,800 people, almost all in West Africa, since it broke out a year ago.
Sierra
Leone, which has overtaken Liberia as the country with the most infections,
counted 9,446 cases and 2,758 deaths on December 28.
Liberia has seen a clear
decrease in transmission over the past month. As of December 28, the country
had recorded 8,018 cases and 3,423 deaths.
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