The
trial is the largest to investigate prostate cancer screening (PA)
|
Routine tests for prostate
cancer do not save lives and have the potential to do more harm than good, a
study has suggested.
Press
Association report continues:
More
than 400,000 men were involved in the trial which looked at the efficacy of
prostate specific antigen (PSA) tests – which are available on request for all
men over 50.
Researchers
said testing men who do not display any symptoms can detect some disease that
would be unlikely to cause any harm and may miss others which can be fatal.
Cancer
Research UK, which funded the research along with the Department of Health,
said: “This highlights the flaws of a single PSA test as a way to screen for
prostate cancer, and shows the need to find more accurate ways to diagnose
cancers that need to be treated.”
The
trial – the largest to investigate prostate cancer screening – compared nearly
190,000 men who were invited for a PSA test and 220,000 who were not.
Researchers
found that after a decade, both groups had the same percentage of men dying
from prostate cancer (0.29%).
Dr
Richard Roope, Cancer Research UK’s GP expert, said: “The PSA test is a blunt
tool missing the subtleties of the disease and causing men harm.
“This
trial illustrates that we need to develop more accurate tools if we want to
save men’s lives.”
Former
BBC Breakfast presenter Bill Turnbull revealed his prostate cancer diagnosis
earlier this week and described his feelings of being in a “dark chasm”.
The
star, 60, had his prostate removed in January after being diagnosed in
December.
Professor
Richard Martin, lead author and Cancer Research UK scientist at the University
of Bristol, said: “Our large study has shed light on a highly debated issue. We
found that offering a single PSA test to men with no symptoms of prostate
cancer does not save lives after an average follow-up of 10 years.
“The
results highlight the multitude of issues the PSA test raises – causing
unnecessary anxiety and treatment by diagnosing prostate cancer in men who
would never have been affected by it and failing to detect dangerous prostate
cancers.
Dr
Emma Turner, a Cancer Research UK scientist at the University of Bristol and
co-author of the study, said: “Prostate cancer is the second most common cause
of cancer death in men in the UK.
“We now need to find better
ways of diagnosing aggressive prostate cancers that need to be treated early.”
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