Friday, May 13, 2016

Nigeria Raises Awareness On Stevens-Johnson syndrome

Minister of Health Professor Isaac Adewole
The Federal Ministry of Health on Friday disclosed that there have been cases of a disease known as Stephens-Johnson syndrome (SJS) in the country but asked Nigerians not to panic.
TheCable report continues:
At a press conference to raise awareness, which had Isaac Adewole, minister of health, in attendance, the ministry disclosed that two cases of SJS had been recorded, resulting in the death of one person in 2012.
Adewole asked Nigerians not to panic.
Boade Akinola, spokeswoman of the ministry, disclosed that a doctor rendering community service was mistakenly infected with HIV.
She said the doctor reacted negatively to the drugs given during treatment, and that led to SJS, which eventually resulted in the death of the health official.
The disease causes the skin of its victim to blister and peel off, leading to the forming of blisters inside the patient’s body.
The victim also finds it hard to eat, swallow, or even urinate.
It starts with fever before symptoms such as watery eyes, sore throat, and fatigue set in.
From research provided by NAIJAGRAPHITTI TEAM, Mayo Clinic in the US provides the following details about  Stephens-Johnson syndrome on its website:
Definition
Stevens-Johnson syndrome is a rare, serious disorder of your skin and mucous membranes. It's usually a reaction to a medication or an infection. Often, Stevens-Johnson syndrome begins with flu-like symptoms, followed by a painful red or purplish rash that spreads and blisters. Then the top layer of the affected skin dies and sheds.
Stevens-Johnson syndrome is a medical emergency that usually requires hospitalization. Treatment focuses on eliminating the underlying cause, controlling symptoms and minimizing complications.
Recovery after Stevens-Johnson syndrome can take weeks to months, depending on the severity of your condition. If it was caused by a medication, you'll need to permanently avoid that drug and others closely related to it.
Symptoms
Stevens-Johnson syndrome symptoms include:
o   Facial swelling
o   Tongue swelling
o   Hives
o   Skin pain
o   A red or purple skin rash that spreads within hours to days
o   Blisters on your skin and the mucous membranes of your mouth, nose, eyes and genitals
o   Shedding of your skin
If you have Stevens-Johnson syndrome, several days before the rash develops you may experience:
o   Fever
o   Sore mouth and throat
o   Fatigue
o   Cough
o   Burning eyes
When to see a doctor
Stevens-Johnson syndrome requires immediate medical attention. Seek emergency medical care if you experience any of the following signs or symptoms:
o   Unexplained widespread skin pain
o   Facial swelling
o   Blisters on your skin and mucous membranes
o   Hives
o   Tongue swelling
o   A red or purplish skin rash that spreads
o   Shedding of your skin
Causes
Stevens-Johnson syndrome is a rare and unpredictable reaction. Your doctor may not be able to identify its exact cause, but usually the condition is triggered by a medication or an infection.
Medication and therapy causes
Drugs that can cause Stevens-Johnson syndrome include:
o   Anti-gout medications, such as allopurinol
o   Pain relievers such as acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve)
o   Medications to fight infection, such as penicillin
o   Medications to treat seizures or mental illness (anticonvulsants and antipsychotics)
o   Radiation therapy
o   Infectious causes
Infections that can cause Stevens-Johnson syndrome include:
o   Herpes (herpes simplex or herpes zoster)
o   Pneumonia
o   HIV
o   Hepatitis
Risk factors
Factors that increase your risk of developing Stevens-Johnson syndrome include:
o   Viral infections. Your risk of Stevens-Johnson syndrome may be increased if you have an infection caused by a virus, such as herpes, viral pneumonia, HIV or hepatitis.
o   Weakened immune system. If you have a weakened immune system, you may have an increased risk of Stevens-Johnson syndrome. Your immune system can be affected by an organ transplant, HIV/AIDS and autoimmune diseases, such as lupus.
o   A history of Stevens-Johnson syndrome. If you've had a medication-related form of this condition, you are at risk of a recurrence if you use that drug again.
o   A family history of Stevens-Johnson syndrome. If an immediate family member has had Stevens-Johnson syndrome or a related condition called toxic epidermal necrolysis, you may be more susceptible to developing Stevens-Johnson syndrome too.
o   Having a certain gene. If you have a gene called HLA-B 1502, you have an increased risk of Stevens-Johnson syndrome, particularly if you take certain drugs for seizures or mental illness. Families of Chinese, Southeast Asian or Indian descent are more likely to carry this gene.
Complications
Stevens-Johnson syndrome complications include:
o   Secondary skin infection (cellulitis). Cellulitis can lead to life-threatening complications, including sepsis.
o   Blood infection (sepsis). Sepsis occurs when bacteria from an infection enter your bloodstream and spread throughout your body. Sepsis is a rapidly progressing, life-threatening condition that can cause shock and organ failure.
o   Eye problems. The rash caused by Stevens-Johnson syndrome can lead to inflammation in your eyes. In mild cases, this may cause irritation and dry eyes. In severe cases, it can lead to extensive tissue damage and scarring that results in blindness.
o   Damage to internal organs. It's unusual for this condition to affect internal organs. But it may cause inflammation of the lungs, heart, kidneys or liver.
Permanent skin damage. When your skin grows back following Stevens-Johnson syndrome, it may have abnormal bumps and coloring. And you may have scars. Lasting skin problems may cause your hair to fall out, and your fingernails and toenails may not grow normally.

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